Fig. 2: Newly identified sperm-specific and disease-linked axonemal proteins.
From: Structural diversity of axonemes across mammalian motile cilia
a, Thirty-four newly assigned axonemal proteins are identified in this study, including 21 ‘general’ proteins that are conserved across cell types (blue) and 13 that are sperm specific (pink). Note that CCDC63, DNAH8, DNAH17 and RSPH6A were previously found to be sperm-specific axonemal proteins but are included here for emphasis. b, Proteins implicated in infertility and other motile ciliopathies are colour coded by whether their disruption in humans or model organisms causes defects in sperm flagella (red), other motile cilia (yellow) or both (orange).
