Extended Data Fig. 2: Bilateral photoinactivation of ALM and TJM1, but not TJS1, reduces lick pathlength and duration.
a, Rhythm of lick bouts are unaffected by spout displacement on L2. Inter-lick intervals (ILI) for L2 to L3 (dark grey) do not significantly differ by condition. ILI for L1 to L2 (light grey), where no spout displacements occurred, provided for comparison. b-d, Left, Cumulative probability of L3 protrusion relative to L2 contact onset for ALM (blue, b), TJM1 (green, c) and TJS1 (brown, d) inactivated trials, relative to no laser trials for the same mice (black). Right, L3 protrusion probability for inactivation and no laser trials. e-j, Effect of bilateral ALM, TJM1 or TJS1 inactivation on L3 lick kinematics. L3 contact probability (e), corrective submovement (CSM) probability (f), lick duration (g), lick pathlength (h), lick peak speed (i) and number of acceleration peaks (j) for left, centre and right trials. Colours for each panel are the same as in b-d. Note that ALM and TJM1, but not TJS1, inactivation impair lick duration and pathlength. Data in e-j are median ± IQR. *corrected p < 0.05, **corrected p < 0.01, two-sided hierarchical bootstrap test; n.s., not significant. Exact statistics are in Supplementary Tables 1, 3 and 4.
