Extended Data Fig. 5: The EfPiwi-piRNA-target RNA (25 nt) ternary complex undergoes the conformational transition from the “comma-shaped” to “locked” state after adding EmGTSF1WT. | Nature

Extended Data Fig. 5: The EfPiwi-piRNA-target RNA (25 nt) ternary complex undergoes the conformational transition from the “comma-shaped” to “locked” state after adding EmGTSF1WT.

From: Structural insights into RNA cleavage by PIWI Argonaute

Extended Data Fig. 5

a-f, Reconstructions of the EfPiwi-piRNA complex (a), EfPiwi-piRNA-target (16 nt) complex (b), EfPiwi-piRNA-target (25 nt) complex in the “comma-shaped” state (c) and in the “locked” state after the EmGTSF1WT addition (d), and still in the “comma-shaped” state after the EmGTSF1Q22A/R25A/K32A/K35A (e) or EmGTSF1W100A/W109A (f) addition.

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