Extended Data Fig. 9: Comparison of overall structures.
From: Structural insights into RNA cleavage by PIWI Argonaute
a, Superposition of PIWI-clade Argonautes’ structures (HILI, PDB: 7yfx; MILI, PDB: 7ygn; EfPiwi, PDB: 7kx7; Siwi, PDB: 5guh; DmPiwi, PDB: 6kr6). b, Superposition of AGO-clade Argonautes’ structures (hAgo1, PDB: 4kxt; hAgo2, PDB: 4w5n; hAgo3, PDB: 5vm9; hAgo4, PDB: 6oon). c, Superposition of MILI (blue) and hAgo2 (green). d, Superposition of MILI (blue) and TtAgo (light brown) (PDB: 3dlh). Structural differences in their N and PAZ domains are indicated by red arrows.
