Extended Data Fig. 9: TBC1D4 haplotypes in Greenland and 1KG-JPT.
From: Genetic architecture in Greenland is shaped by demography, structure and selection
Haplotype plot of the genomic region around the variant in TBC1D4 for Greenlandic heterozygous carriers (n = 116) and the Japanese individual (JPT) from 1KG carrying the variant. For the Greenlandic individuals, their haplotypes without the TBC1D4 variant are shown on top and their haplotypes with the variant are shown on the bottom. Grey means reference allele, blue means alternative allele, and orange/red highlight the TBC1D4 variant. Since the variant is tri-allelic, the Japanese individual did not have phasing information for that variant. Notice that the japanese individual matches haplotypes without the TBC1D4 variant and not the haplotype with the variant which suggests that it is a recurrent mutation.
