Extended Data Fig. 5: Number of non-causal variants in clinical screening setting. | Nature

Extended Data Fig. 5: Number of non-causal variants in clinical screening setting.

From: Genetic architecture in Greenland is shaped by demography, structure and selection

Extended Data Fig. 5

a, Mean number of non-causal pLoF variants remaining after removing variants with given frequency in gnomAD. The dashed blue line is the Greenlandic population after removing variants with above given frequency in either gnomAD or in the Greenlandic reference. b, same as panel a, but only for the Greenlandic population at two different fixed gnomAD-MAF thresholds and varying MAF threshold (x-axis) in the Greenlandic reference.

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