Extended Data Fig. 4: ATAC-seq identifies cell-type- and region-specific transcription factor motifs.
From: Sensory input, sex and function shape hypothalamic cell type development
(a) Differentially accessible regions (DARs) of chromatin specific to each cell type. (b) Cell-type-specific transcription factor motif enrichment, identified from cell-type-specific DARs. Motifs and cell types discussed in the main text are highlighted in red. Motif enrichment determined by hypergeometric test (Methods). (c) Examples of transcription factor motifs in accessible chromatin (ATAC-seq data) enriched amongst anatomical sub-regions that match with region-specific gene expression.
