Extended Data Fig. 9: Extrusive- but not cohesive-cohesin facilitates chromatin individualization.
From: Extensive mutual influences of SMC complexes shape 3D genome folding
a, KR-balanced Hi-C contact matrices showing the trans-chromosomal interactions among chromosomes 1 to 6 in mitotic cells with eight distinct SMC protein complex configurations. Maps of independent clones were shown. Scale bars were normalized to the respective size of each library. b, Bar graph showing the percentage of trans contacts in mitotic cells with eight distinct SMC protein complex configurations. Data are presented as mean values +/- SEM (n = 2 and 3 biological replicates for condensin replete and deficient conditions respectively). P values were calculated using two-sided student’s t-test.
