Extended Data Table 4 Single-dose pharmacokinetic properties of JNJ-9676 in rat, Syrian golden hamster, dog and cynomolgus monkey (after intravenous oral [po] administration) and viral load and infectious virus reduction in Syrian golden hamsters

From: A small-molecule SARS-CoV-2 inhibitor targeting the membrane protein

  1. BID, twice daily; mpk, milligrams/ per kilogram body weight; SARS-CoV-2, severe acute respiratory syndrome coronavirus; TCID50, 50% tissue culture infective dose.