Fig. 5: Driver mutations.
From: The somatic mutation landscape of normal gastric epithelium
a, Number of mutations, broken down by functional effect, for genes under significant positive selection. b, dN/dS ratios for genes under positive selection, broken down by type. c, Heatmap of distribution of specific driver mutations per donor. d, Phylogenetic tree of donor PD42790 (80, M) from the WGS data of individual glands, annotated with putative driver mutations, along with histology images from two regions overlaid with driver mutations and their VAF, of both whole-genome sequenced microdissections (indicated by WGS) and panel-sequenced clusters of microdissections. Scale bars, 1 mm.
