Extended Data Fig. 5: Correlations between mitochondrial parameters assayed using different techniques.
From: A human brain map of mitochondrial respiratory capacity and diversity
a, CS activity and mtDNA density, which are both related to mitochondria mass, are positively correlated. Because of the high variability in MitoTracker Deep Red measurements (MTDR, a far-red fluorescent probe used to chemically mark and visualize mitochondria in cells), they correlated poorly with CS and mtDNA, thus MTDR was not used for further analysis. b and c, Relationship between CII and CIV activities measured by colorimetric and respirometry assays. d, Correlations between CI, CII and CIV activities (an average between colorimetric and respirometry assays). a-d, Pearson’s r2 values show how well datapoints follow the linear regression; p values indicate if the slope of the regression line is significantly different from zero; shaded areas represent 90% confidence interval. e, Relationship between TRC, MRC and MitoD values (see Fig. 2a for definitions) in gray and white matter voxels. *** - the slopes of linear regressions are different with p < 0.001.
