Fig. 7: Subterminal heterochromatin analyses.
a, Overall quantification of subterminal pCht and α-satellites in the African great ape and siamang genomes for haplotypes 1 and 2. The number of regions containing the satellite is indicated below the species acronym. The pCht arrays of diploid genomes are quantified by megabases, for ones located in the p arm, the q arm and the interstitial region. b,c, Organization of the subterminal satellite in gorillas (b) and the Pan lineages (c). The top shows a StainedGlass alignment plot indicating pairwise identity between 2-kb-binned sequences, followed by the higher order structure of subterminal satellite units, as well as the composition of the hyperexpanded spacer sequence and the methylation status across the 25 kb upstream or downstream areas of the spacer midpoint. The average per cent of CpG methylation is indicated as a blue line, and the band of lighter blue represents the s.d. of the methylation. d, Size distribution of spacer sequences identified between subterminal satellite arrays. e, Methylation profile of the subterminal spacer SD sequences compared to the interstitial orthologue copy.
