Extended Data Fig. 6: Biological roles of PROX–HOX2 composite motifs.
From: DNA-guided transcription factor interactions extend human gene regulatory code
Composite motifs of PROX–HOX2 that contain a constitutive activator domain drive highly specific expression of lacZ reporter gene in the apical ectodermal ridge, forebrain, midbrain, hindbrain, facial mesenchyme and otic vesicle of transgenic E11.5 mouse embryos.
