Extended Data Fig. 4: Cryo-EM data processing of the wild-type POLγ dataset. | Nature

Extended Data Fig. 4: Cryo-EM data processing of the wild-type POLγ dataset.

From: Small molecules restore mutant mitochondrial DNA polymerase activity

Extended Data Fig. 4

a, Cryo-EM processing workflow in cryoSPARC for wild-type POLγ, with representative images of micrographs and 2D classification averages. b, FSC resolution at the 0.143 GSFSC threshold as reported by cryoSPARC for the wild-type POLγ map. c, Orientation distribution plot. d, Local resolution estimation calculated by cryoSPARC (FSC threshold = 0.5).

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