Extended Data Fig. 6: Control analysis for the interareal connectivity prediction.

a, iEEG PPC analysis of task-irrelevant trials did not reveal any significant category-selective synchrony cluster in posterior (top) or PFC (bottom) ROIs after removing the evoked response. Same conventions, sample size and statistical tests as in Extended Data Fig. 5 are used here and below. b, MEG PPC analysis of task-irrelevant trials also did not reveal any synchrony cluster in any ROI after removing the evoked response. c, iEEG DFC analysis of task-irrelevant trials without removing the evoked response reveals significant content-selective connectivity between object-selective electrodes and V1/V2 electrodes (top-right), reflected as broadband (25–125 Hz) decrease in the change in DFC (e.g., faces < objects). Similar broadband changes in DFC (faces > objects) were observed for face-selective electrodes in PFC (bottom-left). Smaller significant effects were detected between face-selective and V1/V2 electrodes (top-left) and for object-selective and PFC electrodes (bottom-right). d, MEG DFC analysis of task-irrelevant trials without removing the evoked response reveal significant content-selective synchrony between the face-selective GED filter node and both V1/V2 (top-left) and PFC (bottom-left). This is reflected in an increase in low-frequency connectivity (< 25 Hz) combined with a decrease in high-frequency connectivity (25–100 Hz). Smaller yet significant effects were detected for the object-selective GED filter (right). e, Generalized psychophysiological interactions (gPPI) task-related connectivity analysis of task-irrelevant (left) and task-relevant (right) trials revealed weak clusters of content-selective connectivity with FFA as the analysis seed (p < 0.01, uncorrected). Common significant regions showing task-related connectivity in task-irrelevant, task-relevant, and combined conditions include V1/V2, right intraparietal sulcus (IPS), and right inferior frontal gyrus (IFG). f, gPPI task-related connectivity analysis of task-irrelevant (left), task-relevant (middle), and combined conditions revealed weak clusters of content-selective connectivity with lateral occipital complex (LOC) as the analysis seed (p < 0.01, uncorrected). Overall, no common significant regions showed task-related connectivity. Brain surfaces in panel e, f are from Freesurfer.