Extended Data Fig. 1: Retrieval of a contextual cold memory increases core body temperature.
From: Cold memories control whole-body thermoregulatory responses
a Diagrammatic representation of experimental timeline. b Time plot of core body temperature between mice during Baseline 1 (21 °C; yellow), Test 1 (21 °C; light blue) and Cold 1 (4 °C; dark blue). Comparison of core body temperature between mice during Baseline 1 (21 °C; yellow), Test 1 (21 °C; light blue) and Cold 1 (4 °C; dark blue) at c, hour 2 d, hour 4 e, hour 6 and f, total time averaged in metabolic cages. g Time plot of the change in core body temperature between mice during Baseline 1 (21 °C; yellow), Test 1 (21 °C; light blue) and Cold 1 (4 °C; dark blue) normalized to the average core body temperature on BL1. Time plot of the change in core body temperature between mice during Baseline 1 (21 °C; yellow) and Test 1 (21 °C; light blue) during h, the total 2 h i, the total 4 h and j, total time averaged in metabolic cages. b-j Data shown as mean ± SEM, n = 4 mice per group. c-f, Repeated measures ANOVA. h-j, Paired t-test. *p < 0.05, **p < 0.01, ****p < 0.0001. h, hour; BL1, baseline 1; CL1, Cold 1; T1, Test 1. Schematics in a created with BioRender (https://biorender.com).
