Extended Data Fig. 4: Phylogenetic analysis of Cer1P biosynthesis genes in human gut microbiota.
From: Targeting symbionts by apolipoprotein L proteins modulates gut immunity
a and b, The distribution of key gene orthologues involved in Cer1P biosynthesis, including serine palmitoyltransferase (BT_0870), keto-reductase (BT_3075), ceramide synthase (BT_3032), and ceramide kinase (BT_0871), across fifty-two human commensal bacterial strains (a) used in this study or gut microbiota species (b) from the NIH Human Microbiome Project (HMP) database. c, Coomassie blue staining of purified recombinant his-tagged WT or kinase-dead B. thetaiotaomicron ceramide kinase (BT_0871) protein. Data are representative of two independent experiments (c). For gel source data, see Supplementary Fig. 2.
