Correction to: Nature https://doi.org/10.1038/s41586-025-08850-1 Published online 16 April 2025

In the version of the article initially published, in the “EP300 regulation executes zonal transcription” section, the sentence “We identified HIF1A, TBX3 and AHR as top motifs co-occupied by EP300 in Z3-HLOs, whereas TET1, NRF1 and TFEB were top motifs in Z3-HLOs” should have read “We identified HIF1A, TBX3 and AHR as top motifs co-occupied by EP300 in Z3-HLOs, whereas TET1, NRF1 and TFEB were top motifs in Z1-HLOs”. This error occurred during the editorial process after acceptance of the article and has now been corrected in the HTML and PDF versions of the article.