Extended Data Fig. 1: Choice of mutagenesis strategy. | Nature

Extended Data Fig. 1: Choice of mutagenesis strategy.

From: In vivo mapping of mutagenesis sensitivity of human enhancers

Extended Data Fig. 1

(A) Size distribution of all JASPAR TF binding motifs. (B) Visualization of in silico mutagenesis schemes. (C) Relative score of matches between original TF PWM and mutagenized sequence. (D) Match score min-max normalized to that of best and worst sequence for a given TF PWM. See text for details. Observations are ordered on x-axis by score, so each position does not correspond to the same TF PWM.

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