Extended Data Fig. 6: Assignment of mutational signatures and estimation of telomere length using data from control and PM2.5-exposed mice.
From: The mutagenic forces shaping the genomes of lung cancer in never smokers
a,b, Box plots comparing the mutations assigned to SBS5 (a) and the estimations for the telomere length ratio between the tumour and normal samples (b). Two-sided Student’s t-tests were used to calculate statistical significance. The line within the box indicates the median, the upper and lower ends indicate the 25th and 75th percentiles, and whiskers show 1.5 × interquartile range. n = 5 (control mice) and n = 5 (PM2.5-exposed mice); data from a previous study49.
