Extended Data Fig. 6: Gene mutation mechanisms.
From: Sperm sequencing reveals extensive positive selection in the male germline
a, dN/dS ratios for sperm SNVs across germline selection genes and cancer gene census genes split by ten canonical cancer pathways, where the dotted black line indicates neutrality and the dotted orange line represents the cohort average across all genes. b, The mutation mechanism assigned to each gene based on the mutation pattern in sperm, developmental disorders, and cancer (Methods).
