Extended Data Fig. 4: Cryo-EM data processing of NCLX without calcium at low pH. | Nature

Extended Data Fig. 4: Cryo-EM data processing of NCLX without calcium at low pH.

From: Structure and mechanism of the mitochondrial calcium transporter NCLX

Extended Data Fig. 4

a, A flowchart of NCLX without calcium at low pH data processing. Conformational states of protomers: Class 4b, three in cytosol-facing conformation. Final map gold-standard FSC curves and angular particle distribution are shown next to the local resolution map. b, A representative cryo-EM image (from 9,653 micrographs with similar results). c, Typical 2D class averages. d, Map vs. model FSC. e, Cryo-EM density corresponding to model.

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