Extended Data Fig. 2: Comparison between mTORC1-Rheb on membrane and in solution and Representative cryo-EM density of the active sites of Rag GTPases. | Nature

Extended Data Fig. 2: Comparison between mTORC1-Rheb on membrane and in solution and Representative cryo-EM density of the active sites of Rag GTPases.

From: Structural basis for mTORC1 activation on the lysosomal membrane

Extended Data Fig. 2

a, Asymmetric units of apo mTORC1, mTORC1-Rheb in solution, and mTORC1-Rheb on membrane are aligned based on the mTOR subunit. The rotational direction of Raptor subunit between soluble and membrane-bound mTORC1-Rheb is indicated with an arrow. Cryo-EM density of RagA (b) and RagC (c) at contour level 0.25 and level 0.2, respectively.

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