Extended Data Fig. 3: Islet e-Mac shows similarity with pathology-associated macrophages from other tissues.
From: Efferocytic remodelling of pancreatic islet macrophages by limited β-cell death
a. UMAP plots show scRNASeq of islet macrophages (C57BL/6 mice) and two publicly available scRNASeq datasets: i) microglia in the brain of an Alzheimer’s disease mouse model (GSM7049631 (ref. 36)), and ii) macrophages in adipose tissue of mice fed a high-fat-diet (GSE128518 (ref. 37)). Expression of some marker genes are shown on the right. b. Venn diagram illustrates overlaps among gene signatures from macrophage subsets in (a).
