Supplementary Figure 10: COG distribution in the core genome and the dispensable genome.
From: 1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses
The percentage of 20 COGs in the core genome (pink) was compared to that in the pan-genomes (cyan) of 38 clusters. The significance of improvement was determined by two-side Wilcoxon rank-sum test (*,P< 0.05; **, P < 0.01; ***, P < 0.001). The exact P value is 0.931 for D, 2.70×10-9 for M, 3.11×10-5 for N, 7.28×10-12 for O, 3.88×10-4 for T, 1.22×10-7 for U, 7.28×10-12 for V, 7.28×10-12 for J, 3.64×10-11 for K, 7.28×10-12 for L, 7.28×10-12 for C, 0.261 for G, 7.28×10-12 for E, 7.28×10-12 for F, 1.46×10-11 for H, 2.40×10-10 for I, 0.874 for Q, 2.40×10-10 for P, 0.365 for R, and 0.031 for S. Each boxplot illustrates the estimated median (centre line), upper and lower quartiles (box limits), 1.5 × interquartile range (whiskers), and outlier (points) of the COG percentage.
