Supplementary Figure 6: Antitumor specific lysis of CART.BiTE against EGFR-expressing tumor.
From: CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity
Cytotoxicity of UTD cells (black) or CART-EGFRvIII.BiTE-EGFR cells (orange) against U87 by bioluminescence-based assay at indicated E:T ratios after 18 h. The assay was performed in triplicate, n = 3 biologically independent wells (mean + SEM is depicted).
