Fig. 2: Offspring of the genome-edited polled bull and controls.
From: Genomic and phenotypic analyses of six offspring of a genome-edited hornless bull
Shown are the six offspring and six contemporary controls at <3 months of age (before any horn development) and their parents. a, Study group GH.H.: the genome-edited polled bull (RCI002) was bred to Horned Hereford cows (RC.dams1–6) and produced six polled offspring (RC.calves1–6). b, Study group H.H.: Horned Hereford bulls (HH.sire1 and HH.sire23) bred to Horned Hereford cows (HH.dams1–3) by artificial insemination or natural service produced three horned offspring (HH.calves1–3). c, Study group Ho.H.: the Horned Holstein sire (HO1) of the genome-edited polled bull in a was bred to Horned Hereford cows (HO1.dams1–3) by artificial insemination and produced three horned offspring (HO1.calves1–3). PC designates the Celtic POLLED allele (dominant), PC* designates the additional introgression of the HDR donor plasmid along with the PC Celtic allele and p designates the wild type HORNED allele (recessive). Offspring are labeled as male or female by blue and pink symbols, respectively. All pictures are of the actual animals, with the exception of the two Horned Hereford bulls, for which the images are representative.
