Supplementary Figure 7: Goodness-of-fit partially explains different performance of PCC and treeClust.
From: Co-regulation map of the human proteome enables identification of protein functions
This figure complements Fig. 2i. Systematic comparison of mean absolute errors (MAEs) from protein pairs that scored high with either treeClust or with PCC (see Supplementary Fig. 6a; n = 8,786 treeClust-specific protein pairs, n = 9,593 PCC-specific protein pairs). Protein pairs exclusively detected by PCC tend to have somewhat higher MAEs, possibly explaining why they are predominantly false-positive hits, in addition to the impact of outliers.
