Supplementary Figure 8: Kinase network topologies associated to drug responses.

Association between edge enrichment and drug response by Spearman correlation. The kinase axes showing greater importance to the statistical learning models shown in Fig. 4 were plotted as a function of responses of 36 primary AML cells to the named kinase inhibitors (each data point represents the quantification of the named edge in a primary sample and thus, because of missing data points from Casado et al. (Leukemia 32, 1818-1822, 2018), sample size are edge specific).