Extended Data Fig. 4: Detection of integrated HHV-6A genomes by FISH.
From: Left-handed DNA-PAINT for improved super-resolution imaging in the nucleus
FISH was performed on HEK293T cells harboring two copies of an integrated HHV-6A genome as described previously18. The two viral integration sites were detected in the cell nuclei using HHV-6A specific probes by FISH, matching the detection using the DNA-PAINT approach, and could be successfully reproduced in 30 independent FISH experiments. Scale bar is 2 µm.
