Extended Data Fig. 5: Localization of R-DNA and L-DNA imagers in the nucleus of FISH samples.
From: Left-handed DNA-PAINT for improved super-resolution imaging in the nucleus
R-DNA imagers strongly localize to the nucleus of FISH samples, both without DNA-FISH probes and with DNA-FISH probes coupled to complementary R-DNA binders. L-DNA imagers are not detected in the FISH samples omitting the FISH probes, but show specific loci where the samples are labeled with DNA-FISH probes. Scale bars are 5 µm. All images are reconstructed from 5000 frames and 2 nM imager concentrations.
