Extended Data Fig. 2: Marker Alignment.
From: Nanopore sequencing and the Shasta toolkit enable efficient de novo assembly of eleven human genomes
A marker alignment represented as a dot-plot. Elements that are identical between the two sequences are displayed in green or red - the ones in green are the ones that are part of the optimal alignment computed by the Shasta assembler. Because of the much larger alphabet, matrix elements that are identical between the sequences but are not part of the optimal alignment are infrequent. Each alignment matrix element here corresponds on average to a 13 13 block in the alignment matrix in raw base sequence.
