Supplementary Fig. 9: Time dynamics of the frequency of SDGDdsx as function of male fitness.
From: A male-biased sex-distorter gene drive for the human malaria vector Anopheles gambiae
Time dynamics of the frequency of SDGDdsx transgenic individuals in the population as a function of the fitness of SDGD males (assume wWD,xY = wDR,xY = wDD,xY) as predicted by the deterministic discrete-generation model. Initial release is 50% of SDGD heterozygote males and females as a proportion of the male (or female) population, with other parameter estimates and baseline values given in Supp Table 2 (W/D female fitness wWD,xx = 0.627; m = 0.93). For low SDGD male fitness (<≈0.5), the construct is eventually lost.
