Extended Data Fig. 2: Indel frequencies of nCas9 controls, ABE variants and CBE variants tested for C-to-G editing in HEK293T cells. | Nature Biotechnology

Extended Data Fig. 2: Indel frequencies of nCas9 controls, ABE variants and CBE variants tested for C-to-G editing in HEK293T cells.

From: CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells

Extended Data Fig. 2

a, b, Dot plots representing percentage of alleles that contain an insertion or deletion across the entire protospacer from experiments with various base editor architectures reported in (a) Extended Data Fig. 1 for nCas9 controls and ABE variants or (b) Fig. 1b and Extended Data Fig. 1 for CBE variants and CGBE1. Single dots represent individual replicates (n = 3 independent replicates).

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