Extended Data Fig. 9: Comparing the depleted hits of BARBEKO and CRISPR-KO screens in RPE1 cells.
From: Genome-wide interrogation of gene functions through base editor screens empowered by barcoded sgRNAs
a, Venn diagram showing the numbers of commonly and differently selected hits of BARBEKO and CRISPR-KO screens. b-d, GO enrichment analysis by Metascape of common essential hits in wild-type cells but not in TP53-/- cells (b), unique essential hits of BARBEKO screen in wild-type cells (c) and CRISPR-KO screen in wild-type cells (d). GO terms are ranked by the value of FDR from small to large. The size of circle represents the number of genes belonging to each term.
