Extended Data Fig. 8: Comparison of monocyte subtypes between COVID-19, sepsis, and HIV. | Nature Biotechnology

Extended Data Fig. 8: Comparison of monocyte subtypes between COVID-19, sepsis, and HIV.

From: Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19

Extended Data Fig. 8

(a) Summary of metabolic pathway activities for metabolically defined monocyte subtypes in each disease. For the box plots, n = 90 pathways for each condition. Boxes indicate 25th, 50th, and 75th percentiles. Whiskers indicate 1.5 interquartile ranges below and above the 25th and 75th percentiles, respectively. (b) Gene ontology analysis of metabolic genes uniquely elevated in S100A9high inflammatory monocytes of COVID-19, showing only the processes that have greater than fivefold enrichment in the COVID-19 condition.

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