Extended Data Fig. 1: Benchmarking DA methods on simulated data.
From: Differential abundance testing on single-cell data using k-nearest neighbor graphs
DA analysis performance on KNN graphs from simulated datasets of different topologies: (a) discrete clusters (2700 cells, 3 populations); (b) 1-D linear trajectory (7500 cells, 7 populations); (c) Branching trajectory (7500 cells, 10 populations). Boxplots show the median with interquartile ranges (25–75%); whiskers extend to the largest value no further than 1.5x the interquartile range from the distance from the box, with outlier data points shown beyond this range.
