Extended Data Fig. 2: Exercise-and insulin regulated phosphosites, and comparison with phosphoproteomes measured immediately after acute exercise. | Nature Biotechnology

Extended Data Fig. 2: Exercise-and insulin regulated phosphosites, and comparison with phosphoproteomes measured immediately after acute exercise.

From: Personalized phosphoproteomics identifies functional signaling

Extended Data Fig. 2

a, Volcano plots of the phosphosites regulated by exercise and insulin (two-way repeated measures ANOVA with planned contrasts). b, Upset plot, quantifying the regulated phosphosites (BH padj < 0.05 and fold change > 1.5) shared in the different conditions. c, Quantified phosphosites in this study compared to Hoffman et al. 2015. d, Regulated phosphosites by exercise recovery in this study, not considering the insulin-stimulated states, compared to Hoffman et al. 2015. For this study, regulated is padj < 0.05 and fold change > 1.5. For Hoffman et al., regulated is considered as padj < 0.05. e, Enrichment of kinase substrates in the ground state exercise-regulated phosphosites in this study compared to Hoffman et al. regulated phosphosites.

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