Extended Data Fig. 3: Performance metrics for DNA methylation profiling with FAST5 / SLOW5 files. | Nature Biotechnology

Extended Data Fig. 3: Performance metrics for DNA methylation profiling with FAST5 / SLOW5 files.

From: Fast nanopore sequencing data analysis with SLOW5

Extended Data Fig. 3

(a,b) Dot plots show the rate of data processing (reads / second) during DNA methylation calling with ASCII SLOW5 (purple), binary BLOW5 (orange), BLOW5-zlib (red) and FAST5-zlib (blue) files as a function of CPU threads. Analysis was performed on two HPC architectures: HPC-HDD (a) or HPC-Lustre (b; see Supplementary Table 2). (c,d) Dot plots show the ratio of data-processing time relative to total execution time for the jobs above. (e,f) Bar charts show the proportional CPU utilisation (e) and total core hours (f) during the DNA methylation calling with BLOW5-zlib on the HPC-HDD system. The definition of core-hours is provided in the Methods section.

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