Extended Data Fig. 5: Determination of peptide structures using circular dichroism (CD) spectra.
From: Identification of antimicrobial peptides from the human gut microbiome using deep learning
a, CD results for the 11 most potent peptides and b, corresponding proportions of secondary structures calculated from CD data using CDNN. Purple: in water phase; dark blue: peptide mixed with 20 times of DMPE/DMPG lipid mixture (see Methods). c, and d, Further CD results and predicted structures of 11 randomly selected peptides with AMP activity. e, positive control Magainin 2, with CD results (left), predicted proportions of each secondary structure (middle) and known structure in PDB (right, accession no. 2LSA).
