Extended Data Fig. 1: Exon transcript profiles of P cells.
From: High-throughput functional evaluation of human cancer-associated mutations using base editors
a, Expression of TP53 mRNA in P cells and HBEC30KT cells. FPKM, fragments per kilobase of transcript per million. Boxplots are represented for n = 3 biologically independent samples as follows: center line of box indicating the median, box limits indicating the upper and lower quartile; whiskers show the 1.5 times interquartile range. b, Gene set enrichment analysis (GSEA) of exon transcript profiles of HBEC30KT, P cells, and HCC4017, a lung cancer cell line. The single sample GSEA score (ssGSEA score) represents the degree to which the genes in a particular gene set are up- or down-regulated within the sample. RNA expression data were retrieved from Kim et al34.
