Extended Data Fig. 4: Effects of RBD and sensor titration on detecting SARS-CoV-2 antibodies. | Nature Biotechnology

Extended Data Fig. 4: Effects of RBD and sensor titration on detecting SARS-CoV-2 antibodies.

From: Thermodynamically coupled biosensors for detecting neutralizing antibodies against SARS-CoV-2 variants

Extended Data Fig. 4

a,b, Resulting fraction of lucCageRBD dynamic range lost (a) and lucCageRBD EC50 (b) from different concentrations of mAb CV30 with different concentrations of RBD WT in 1 nM of RBD sensor and lucKey. c-d, Resulting fraction of lucCageRBD dynamic range lost (c) and lucCageRBD EC50 (d) from different concentrations of mAb CV30 with different concentrations of RBD sensor and lucKey (1:1 stoichiometry maintained) and with 5 nM RBD. All experiments were performed in triplicates and data are mean ± s.e.m.

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