Extended Data Fig. 2: Probabilistic model of gene expression and allele counts from transcriptome sequencing experiments.
From: Haplotype-aware analysis of somatic copy number variations from single-cell transcriptomes
cm, number of maternal chromosome copies. cp, number of paternal chromosome copies. λi, observed gene expression magnitude of gene i. \(\lambda _i^ \ast\), reference gene expression magnitude of gene i. μ and σ2, global bias and variance in gene expression. πj, fraction of paternal alleles of SNP j. γ, global inverse overdispersion of allele-specific detection. l, library size. mj, total allele count of SNP j. Xi, observed molecule counts for gene i. Yj, observed paternal allele count for SNP j.
