Extended Data Fig. 2: Intestinal cell lineage expression in HIO transplanted in humanized mice. | Nature Biotechnology

Extended Data Fig. 2: Intestinal cell lineage expression in HIO transplanted in humanized mice.

From: In vivo development of immune tissue in human intestinal organoids transplanted into humanized mice

Extended Data Fig. 2

a-d. Co-staining of intestinal markers (red), human CD45 (green) and human CDH1 (white) on sections of HIOs at 12, 16 and 20 weeks post transplantation in humanized mice. Images represent presence of enterocytes (VIL/Villin) (a), goblet cells (MUC2/Mucin2) (b), Paneth cells (LYZ/Lysozyme) (c) and enteroendocrine cells (CHGA/Chromogranin A) (d). Scale bar represents 100 µm. Representative of 2 independent experiments.

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