Extended Data Fig. 6: Randomly selected examples of cell-type-specific predictions from Akita, DeepC, Orca and C.Origami.

a, Sequence-based model predictions, b, C.Origami prediction with IMR-90-specific genomic features (CTCF ChIP–seq and ATAC–seq) and IMR-90 experimental Hi-C. c, C.Origami de novo prediction with GM12878-specific genomic features and GM12878 experimental Hi-C. All presented results were aligned at randomly selected regions from different chromosomes. The full set of prediction results across all cell-type-specific chromatin regions between IMR-90 and GM12878 cells were included in the Supplementary material under Cell-type-specific predictions.