Extended Data Fig. 3: CD21 expression on human splenic B cells in CV-BLT and GF-BLT mice.

CD21 expression was evaluated on human B cells isolated from the spleen of CV-BLT (n = 5, black) and GF-BLT (n = 5, red) mice using flow cytometry. The a, percent of human B cells expressing CD21 and the b, mean fluorescent intensity (MFI) of CD21 staining on CD21+ human B cells was compared between CV-BLT and GF-BLT mice with a two-sided Mann-Whitney test. Horizontal and vertical lines represent the mean and standard error mean respectively.