Extended Data Fig. 6: Filtration of screening data by sensor editing efficiency.
From: High-throughput evaluation of genetic variants with prime editing sensor libraries
The LFC of a, pegRNAs ≥ 0% editing b, pegRNAs ≥ 20% editing c, pegRNAs ≥ 40% editing d, pegRNAs ≥ 60% editing, with at least 10 sensor reads at Day 34 relative to Day 4 in the Nutlin-treated condition, with pegRNAs colored by editing efficiency (left) and colored by variant type (right). Selected enriching pegRNAs with FDR < 0.05 labeled and depleting pegRNAs with FDR < 0.05 labeled. Blue = SNV, Green = INS, Purple = DEL, Gray = Silent.
