Extended Data Fig. 4: Microdissected stromal and tumor core areas. | Nature Biotechnology

Extended Data Fig. 4: Microdissected stromal and tumor core areas.

From: Identification of clinically relevant T cell receptors for personalized T cell therapy using combinatorial algorithms

Extended Data Fig. 4

a) Representative example of the frequency of annotated CD8+ T-cell clones specific for TAAs, neoantigens or viral peptides in the microdissected stromal and tumor core areas of patient 2. Frequencies are displayed in logarithmic scale. b) Cumulative frequencies of annotated CD8+ T-cell clones specific for TAAs, neoantigens or viral peptides in the microdissected stromal and tumor core areas of five melanoma patients (1–5, Supplementary Table 3). Frequencies are displayed in logarithmic scale and statistics were performed using a one-tailed Chi-square test.

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