Extended Data Fig. 2: CRC cells outcompete the healthy epithelium and expand throughout the mini-colon.
From: Patient-derived mini-colons enable long-term modeling of tumor–microenvironment complexity
a, Brightfield time-course images of a healthy mini-colon without cancer cells. Scale bar, 100 μm. b, Fluorescence time-course images of a mini-colon bearing patient #NW CRC cells. Red and green fluorescence signal indicate healthy and cancer cells, respectively. Scale bar, 100 μm. c, Brightfield time-course images of conventional organoid cultures generated from the same mix of CRC and healthy colon cells that is used for the establishment of CRC mini-colons (patient #NW). Scale bar, 100 μm.
