Fig. 1: Schematic of ACE and its applications.
From: Signal amplification by cyclic extension enables high-sensitivity single-cell mass cytometry
a, Schematic of the ACE approach for signal amplification in mass cytometry analysis. b, ACE amplifies the signal in suspension mass cytometry, allowing detection and quantification of low-abundance markers that do not reach detection limits of a mass cytometer using conventional approaches. c, Coupled with IMC, ACE enables high-sensitivity multiparametric spatial profiling of healthy and diseased tissue samples.
